Raman spectroscopy protocol analyses individual nanoparticles published in Nature Communications
Monday, October 15, 2018
The Stevens Group’s latest Nature Communications article entitled “Single Particle Automated Raman Trapping Analysis" reports on how Raman spectroscopy can be exploited to analyse nanoparticles on a single particle basis, without the need for labelling steps or sequential imaging steps, using a technique called SPARTATM. Stevens Group members Jelle Penders, Isaac Pence, Conor Horgan, Mads Bergholt, Chris Wood, Adrian Najer, Ulrike Kauscher and Anika Nagelkerke all contributed in a terrific team effort. Well done!
Manuscript published in Science
Friday, May 04, 2018
In the most recent issue of Science, our article entitled “Fractal-like hierarchical organization of bone begins at the nanoscale” is led by former Stevens Group postdoc Dr Natalie Reznikov in collaboration with the group of Prof Roland Kroger at York. This report shows how the fractal organisation of bone was elucidated using state-of-the-art high resolution imaging techniques.
[C&EN highlight] [Imperial news highlight] [Discover magazine highlight] [Nanotechweb highlight]
Manuscript Featured in Advanced Materials
Monday, April 16, 2018
The Stevens Group has been featured on the Back Cover of the most recent issue of Advanced Materials. The report, entitled “Drug Delivery: Engineering Extracellular Vesicles with the Tools of Enzyme Prodrug Therapy”, was led by Dr Gregor Fuhrmann and Drs Rona Chandrawati, Paresh Parmar, Timothy Keane, Sergio Bertazzo and Ms Stephanie Maynard and describes how extracellular vesicles can be incorporated in hydrogels as an advanced enzyme-prodrug therapy.
Manuscript Featured on the Front Cover of ChemBioChem
Thursday, March 08, 2018
The Stevens Group has been featured on the Front Cover of the most recent issue of ChemBioChem. The report, entitled “MicroRNA Detection by DNA-Mediated Liposome Fusion”, was led by Stevens group alumnus Dr Coline Jumeaux and also includes Stevens Group member Eunjung Kim and alumni Rona Chandrawati and Philip Howes, in collaboration with Prof Fredrik Höök and describes how liposome fusion can be mediated by DNA to selectively detect microRNA in low nanomolar concentrations.
Study on cell geometry directing stem cell signalling and fate published in Nature Materials
Friday, February 16, 2018
The Stevens Group’s latest Nature Materials article entitled "Cell-geometry-dependent changes in plasma membrane order direct stem cell signalling and fate" reports on how cell shape and geometry act as regulators for cell physiology and stem cell signalling. Stevens Group members Thomas von Erlach, Sergio Bertazzo, Christine-Maria Horejs, Stephanie Maynard, Hélène Autefage, Charalampos Kallepitis and Silvia Goldoni contributed with excellent studies along with strong collaborations from the del Río Hernández and Chen research labs. Well done!
Ultrasensitive point of care diagnostic test for HIV
Friday, February 02, 2018
The Stevens Group’s paper entitled “Platinum nanocatalyst amplification: Redefining the gold standard for lateral flow immunoassays with ultrabroad dynamic range” reports on an ultrasensitive diagnostic test that outperforms the gold standard point-of-care commercial kit for p24, a biomarker for HIV. This work involved members Colleen Loynachan, Michael Thomas, and Shweta Agarwal and is supported by the EPSRC IRC “i-sense” consortium and our collaborators within “i-sense”.
[Imperial news highlight] [i-sense news highlight]
Ultraspecific diagnostic test for Ebola virus
Thursday, January 18, 2018
The Stevens Group’s paper “A serological point-of-care test for the detection of IgG antibodies against Ebola virus in human survivors” reports on an ultraspecific diagnostic test capable of distinguishing different strains of the Ebola virus in serum from survivors in Uganda. This work involved members Polina Brangel and Philip Howes and is supported by the EPSRC IRC “i-sense” consortium and our collaborators within “i-sense”.
[Imperial Ebola news highlight] [i-sense news highlight][C&EN news highlight]
Chem publication highlighted as GroundBreaking Paper
Wednesday, August 02, 2017
A paper from co-authors Christopher Spicer, Marsilea Booth, Damia Mawad, Astrid Armgarth, Christian Nielsen, and Molly Stevens entitled “Synthesis of Hetero-bifunctional, End-Capped Oligo-EDOT Derivatives” has been highlighted as a “Groundbreaking Paper” by the journal Chem. This report demonstrates an innovative method of synthesising well-defined, stable oligo-EDOTs for applications in tissue engineering.
Manuscript Featured on the Front Cover of Advanced Functional Materials
Wednesday, September 23, 2015
The Stevens Group has been featured on the Front Cover of the most recent issue of Advanced Functional Materials. The report, entitled “Modular and Versatile Spatial Functionalization of Tissue Engineering Scaffolds through Fiber-Initiated Controlled Radical Polymerization”, was led by Ms Rachael Harrison and also includes Stevens Group members Joseph Steele, Robert Chapman, Adam Gormley, Muzamir Mahat and alumnus Lesley Chow and describes a dual-functionality scaffold with a cell-adhesive surface and an opposing antifouling non-cell-adhesive surface.
Nanoneedle-based approach demonstrates extraordinary delivery capabilities in cells and tissues
Monday, March 30, 2015
The Stevens Group’s latest Nature Materials article entitled “Biodegradable silicon nanoneedles delivering nucleic acids intracellularly induce localized in vivo neovascularization” reports an innovative nanomaterial-based device designed for intracellular delivery of sensitive cargoes. The paper by Chiappini et al in collaboration with HMRI describes how nanoneedles based on porous silicon can facilitate the delivery of nucleic acids (e.g. DNA and siRNA) in living cells and tissues non-destructively.
[Front Cover] [Nature News and Views Highlight] [Imperial News Highlight] [IO9 Highlight]
Nanomaterials-based System for Multimodel Imaging and Therapy of Tumors Published in PNAS
Tuesday, February 17, 2015
Stevens Group member Dr Mathew Hembury et al has published a study entitled “Gold-silica quantum rattles for multimodel imaging and therapy” in the latest issue of PNAS! This paper describes the potential of these exciting nanomaterial innovations for applications in imaging and as therapeutic options for cancerous tissues and has been highlighted in Nanotechweb and Nanowerk. We thank The Rosetrees Trust for generous support.
[Nanotechweb Highlight] [Nanowerk Highlight]
Review of Colloidal Nanoparticles as Advanced Biological Sensors published in Science
Friday, October 03, 2014
Stevens Group members Dr Philip Howes and Dr Rona Chandrawati have published a review entitled “Colloidal Nanoparticles as Advanced Biological Sensors” in the latest issue of Science. This Review gives a comprehensive overview of the use of specialised nanomaterials as diagnostic tools and their applications in the global healthcare system. Congrats Phil and Rona!
Study of Nanoparticle Growth Created by Enzyme Nanopatterns on the Front Cover of Adv. Funct. Mater.
Wednesday, June 25, 2014
The Stevens Group has been featured on the Front Cover of the most recent issue of Advanced Functional Materials. The report by former group member Dr Roberto de la Rica and current members Ms Karla L Herpoldt, Dr Hai-nan Xie, Dr Sergio Bertazzo and Prof Molly Stevens entitled “Nanoparticle Growth via Concentration Gradients Generated by Enzyme Nanopatterns” describes the mechanism of nanoparticle growth kinetics as affected by nanoscale patterns of enzymes.
Plasmonic Nanomaterials for Biodiagnostics featured on the Front Cover of Chemical Society Reviews
Saturday, June 07, 2014
The Stevens Group has been featured on the Front Cover of a Nanoplasmonics themed issue of Chemical Society Reviews. The report by Dr Philip Howes, Dr Subinoy Rana and Prof Molly Stevens entitled “Plasmonic nanomaterials for biodiagnostics” describes the state of the art in biosensing research based on plasmonic nanomaterials, which are capable of detecting biomarkers corresponding to various disease states.
Nanoparticle-based assay featured on Front Cover of Chemical Communications
Tuesday, April 29, 2014
The Stevens Group has been featured on the Front Cover of the most recent issue of Chemical Communications. The report by Dr Rona Chandrawati and Prof Molly Stevens entitled "Controlled assembly of peptide-functionalized gold nanoparticles for label-free detection of blood coagulation Factor XIII activity" describes how peptide-functionalized gold nanoparticles assemble specifically in the presence of blood coagulation Factor XIII, which has clinical importance in hemostasis, as components of a sensitive colourimetric assay.
Laminin-111 shown to modulate stem cell transitions
Friday, April 04, 2014
The Stevens Group has published their latest article in PNAS! The paper by Christine-Maria Horejs et al entitled “Biologically-active laminin-111 fragment that modulates the epithelial-to-mesenchymal transition in embryonic stem cells” reports the group’s latest research involving the importance of laminin fragments in stem cell differentiation. We thank the UK Regenerative Medicine Platform Hub “Acellular Approaches for Therapeutic Delivery” for generous support.
Nano-analytical electron microscopy reveals fundamental insights
Thursday, June 13, 2013
The Stevens Group have been featured in C&EN (Chemical & Engineering News) and Materials 360 Online News following the publication of their latest Nature Materials paper. The paper by Bertazzo et al entitled “Nano-analytical electron microscopy reveals fundamental insights into human cardiovascular tissue calcification” features the group’s research implicating nanoscale hydroxyapatite particles in calcification-related cardiovascular disease. We thank The Rosetrees Trust for generous support.
[C&EN Highlight] [Materials 360 Highlight]
Nature Nanotechnology paper
Thursday, November 01, 2012
The Stevens Group have been featured in a variety of media including the Nature highlights following the publication of their latest Nature Nanotechnology paper. The paper by Roberto de la Rica & Molly Stevens entitled “Plasmonic ELISA for the ultrasensitive detection of disease biomarkers with the naked eye” features the group’s latest research developing a test which can detect the presence of HIV biomarkers with the naked eye.
Stevens’ group research featured in ERC brochure
Monday, October 01, 2012
Prof. Molly Stevens’ research project on ‘Nanotechnology to help rebuild bodies and detect disease’ has been featured in the ERC brochure ‘Biotechnology 2012: An insight into ERC projects’. The brochure on Biotechnology features the most innovative grantees' projects as examples of the research ERC is funding.
[Read the brochure here!]
Nature Materials paper reports unique inverse sensing mechanism for ultrasensitive biosensing!
Wednesday, June 27, 2012
The Stevens Group have been featured in a variety of media including the Daily Express, Times of India, Medical Daily and a range of health and medical websites following the publication of their latest Nature Materials paper. The paper entitled “Plasmonic nanosensors with inverse sensitivity by means of enzyme-guided crystal growth” features the group’s latest research about sensors with inverse sensitivity.
[Nature Materials News and Views Highlight] [Nature Asia Highlight] [Physics World Highlight] [Reuters Highlight] [Science Translational Medicine Highlight]
Stevens’ Group Paper highlighted in Chemistry World
Tuesday, April 24, 2012
Congratulations to Dr. Sergio Bertazzo, Mr. Thomas von Erlach, Dr. Silvia Goldoni and Miss Pelin Çandarlıoğlu whose paper entitled “Correlative light-ion microscopy for biological applications” has been featured in a news article in Chemistry World, ‘Two in one technique for biological imaging’.
[Full Text][Chemistry World Highlight]
Prof Stevens featured in The Lancet
Saturday, April 21, 2012
Prof Stevens was interviewed for The Lancet by David Holmes for an article entitled “Molly Stevens: material girl”. In the article Prof. Stevens discusses her current research, and the potential health applications of her group’s work.
Paper by Lijun Ji to feature on the front cover of Chemical Communications
Monday, August 15, 2011
Congratulations to Lijun Ji whose paper entitled “Template synthesis of ordered macroporous hydroxyapatite bioceramics” has been accepted to appear on the front cover of Chemical Communications, Volume 47, Number 32.
Paper by Dr Heiko Andresen and Dr Shalini Gupta selected as one of Chem Comm’s hot papers
Monday, February 07, 2011
A paper by Heiko Andresen and Shalini Gupta entitled "Single-step kinase inhibitor screening using a peptide-modified gold nanoparticle platform" was recently accepted in Chem Comm and has been selected as one of Chem Comm's hot papers.
[Chem Comm blog]
Paper by Oliver Mahony to feature on the front cover of Advanced Functional Materials
Wednesday, November 10, 2010
Congratulations to Oliver Mahony whose paper entitled “Silica-Gelatin Hybrids with Tailorable Degradation and Mechanical Properties for Tissue Regeneration” has been accepted to appear on the front cover of Advanced Functional Materials.
[Full text][Front Cover]
Paper by Dr Caterina Minelli and Mr Stuart Lowe featured on front cover of Small
Monday, October 25, 2010
Congratulations to Caterina Minelli and Stuart Lowe whose paper entitled “Engineering Nanocomposite Materials for Cancer Therapy” has been chosen to feature on the front cover of the journal Small.
[Article available at Wiley Online Library]
Dr Daniel Aili’s paper chosen for front cover of Chemical Society Reviews
Wednesday, October 13, 2010
Congratulations to Daniel Aili whose paper entitled “Bioresponsive peptide–inorganic hybrid nanomaterials” in Chemical Society Reviews has been chosen to appear on the front cover.
[Article available at Chemical Society Reviews]
Article by Daniel Aili and Morgan Mager is Editor’s Choice in Science
Congratulations to Daniel Aili and Morgan Mager whose article "Hybrid Nanoparticle−Liposome Detection of Phospholipase Activity" was highlighted in a News and Views piece in Nature Chemistry and was selected for the Editor's Choice in Science. The article is due to appear in print in the April edition of Nano Letters and will also be featured on that issue's front cover.
Stevens Group Research in Nature News
Tuesday, March 23, 2010
The Stevens Group's research has been featured in Nature News. The article “Nanoparticle kit could diagnose disease early” discusses techniques in which colour changes show the presence of minuscule amounts of key enzymes.
[Nature News Highlight]